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Tapinarof is a therapeutic aryl hydrocarbon receptor-modulating agent (TAMA) indicated for the treatment of adult psoriasis.
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✅ Description:
- Tapisis 1% Cream is used for the topical treatment of mild to moderately severe psoriasis.
- It reduces the red, scaly patches on the skin by lowering the rate at which skin cells grow.
- For external use only.
- Use exactly as prescribed by your doctor.
- Ensure the affected area is clean and dry before application.
- Wash hands thoroughly before and after applying the ointment.
- Use regularly for maximum benefit.
- Do not exceed the prescribed amount to avoid increased side effects.
- Consult your doctor if the condition persists beyond four weeks or worsens.
- Avoid direct contact with eyes. In case of contact, rinse thoroughly with water and seek medical attention.
- Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
- Inform your doctor if you have any kidney or liver diseases for appropriate dosage adjustments.
- Do not use Tapisis 1% Cream on the face to prevent skin irritation.
- Limit or avoid excessive exposure to sunlight or UV light while using this medication.
Safety Advices
Alcohol
UNSAFE
No interaction was found. However, it is advisable not to take or limit alcohol as a precautionary measure.
Pregnancy
CAUTION
Tapisis 1% Cream should not be taken until prescribed. Your doctor will weigh the benefits and potential risks before prescribing it. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
It is not known if Tapisis 1% Cream passes into the breast milk. Please consult your doctor before taking Tapisis 1% Cream if you are breastfeeding. If you need to apply the cream or ointment on your breasts, don't do this shortly before giving a feed.
Driving
SAFE
There have been no studies to investigate the effect of Tapisis 1% Cream on driving performance or the ability to operate machinery.
Kidney
SAFE IF PRESCRIBED
Let your doctor know if you have any history of kidney diseases before taking Tapisis 1% Cream. Your doctor will weigh the benefits and potential risks before prescribing Tapisis 1% Cream.
Liver
SAFE IF PRESCRIBED
Let your doctor know if you have any history of liver diseases before taking Tapisis 1% Cream. Your doctor will weigh the benefits and potential risks before prescribing Tapisis 1% Cream.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Composition of Tapisis 1% Cream
Tapinarof
✔️ Uses of Tapisis 1% Cream
- Psoriasis
✔️ Side Effects of Tapisis 1% Cream
Common adverse reactions (≥ 1% incidence): folliculitis, nasopharyngitis, contact dermatitis, headache, pruritus, and influenza.
✔️ How does Tapisis 1% Cream work?
Tapinarof lowers the rate with which skin cells grow, thereby controlling the psoriatic condition.
✔️ Indication of Tapisis 1% Cream
- Tapisis 1% cream is indicated for the topical treatment of plaque psoriasis in adults.
✔️ Pharmacology
- Contains Tapinarof, an Aryl hydrocarbon Receptor (AhR) agonist.
- The exact mechanisms of its therapeutic action in psoriasis are unknown.
✔️ Dosage & Administration of Tapisis 1% Cream
- Apply a thin layer of Tapinarof cream to affected areas once daily.
- Wash hands after application unless treating the hands.
- Not for oral, ophthalmic, or intravaginal use.
- Pediatric Use: Safety and efficacy in pediatric subjects under 18 years of age have not been established.
✔️ Interaction
No hazardous interactions with other medicines have been reported.
✔️ Contraindications
Hypersensitivity to any component of the cream.
✔️ Pregnancy & Lactation
Pregnancy:
- Insufficient data on use in pregnant women to assess risk.
- Animal studies showed no significant adverse effects at doses 268 times (rats) and 16 times (rabbits) the maximum recommended human dose (MRHD).
- The background risk of major birth defects and miscarriage for the indicated population is unknown.
Lactation:
- No data on the presence of Tapinarof in human milk or its effects on breastfed infants.
- Detected in the milk of lactating rats.
- Likely to be present in human milk if present in animal milk.
- Consider the benefits of breastfeeding along with the mother's need for Tapinarof and any potential adverse effects on the infant.
✔️ Precautions & Warnings
- For external use only.
- Avoid contact with eyes, mouth, and vagina.
- Discontinue use and seek appropriate therapy if an allergic reaction occurs.
✔️ Storage Conditions:
- Store below 30°C in a dry place.
- Protect from light and keep out of the reach of children.
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